The NSF has launched research.gov, their new portal for the comprehensive management of NSF applications and awards. It’s an upgrade of the current Fastlane system and the NSF is phasing in the use of the new portal and phasing out Fastlane.
As of January 2012, reports for current NSF awards are required to be submitted through research.gov instead of Fastlane. Applications are still accepted in Fastlane.
Be sure to read the solicitation announcement to ensure you are sending the application and any future reporting to the correct system. If you have doubts, contact the program officer. Everyone at NSF was incredibly approachable and welcomed contacts.